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Systematic Reviews and Meta Analysis

A resource for finding data sources, filters, and standards to support systematic searches of the biomedical literature.

Handouts and Tools

You can register and use a Covidence project for you search.

These documents are provided in support of the training provided for HSPH classes EPI233 and EPI528.

Suggested Reading

Greyson D, Rafferty E, Slater L, MacDonald N, Bettinger JA, Dubé È, MacDonald SE. Systematic review searches must be systematic, comprehensive, and transparent: a critique of Perman et al. BMC Public Health. 2019 Feb 4;19(1):153. doi: 10.1186/s12889-018-6275-y. PubMed PMID: 30717742.

Ioannidis JP. The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses. Milbank Q. 2016 Sep;94(3):485-514. doi: 10.1111/1468-0009.12210. PubMed PMID: 27620683; PubMed Central PMCID: PMC5020151.

Search Exercises


When are antidepressants used to treat ADHD (attention deficit hyperactivity disorder)? Find Randomized Controlled Trials.


What is the efficacy of rituximab in treating rheumatoid arthritis? Find randomized clinical trials.  Synonyms for rituximab: mabthera, idec c2b8, rituxan.

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